Is it possible to use VIM in large C++11 projects?

I am fluent with vim's keys and use it a lot, especially for automated edits.

But is that possible to set up vim for working with large C++11 codebase with a lot of macros and templates? Can it parse all the 10000 sourcefiles, build (and dynamically rebuild) a complete "index of everything" and autocomplete anything almost as Eclipse does?

Please suggest the best known manual / plugins for using vim in large modern (C++11) projects?